Inhalation Systems

Nano Technology, Dust, Liquid aerosol, Vapor, Cigarette Smoke Generation, Exposure & Analysis

TSE Systems develops and manufactures complete solutions for a variety of inhalation exposure test assays. We offer a wide range of equipment and components for in-vivo and in-vitro studies with aerosols and vapors.

Our exposure systems are suitable for long- and short-term inhalative investigations with test animals or cell cultures involving toxicity and impact of particulate matter, e.g. in pharmacology, environmental and occupational safety, and bio-defense studies.

The exposure system design and Daco inhalation software for automatic control and regulation of experiments support you in achieving compliance with the OECD, EPA and GLP guidelines.

It is our belief that planning an appropriate inhalation system can only be realized in close cooperation with the customer, focusing particularly on the research aim and test substance(s) used. Our extensive experience will contribute to a successful system and laboratory setup design and rapid execution.

Standardized, modular components covering a wide range of exposure instrumentation are configured to form an efficient tool for scientific research in the field of inhalation exposure.

Head Nose Only Units

Flexibility: Our Head Nose Only exposure units have a modular expandable design which allows them to be continually adapted to the customer’s requirements. The structure consists of single segments which can be stacked on top of each other.

We work with top of the class scientists, side by side: The validation of the equilibrium distribution and directed-flow design was carried out in 1994/2007 by Prof. Pauluhn, and in 2009 by Prof. Phalen.

Each Head Nose Only exposure unit can be equipped with the required aerosol inlet interfaces, appropriate exposure tubes, various sampling ports and environmental sensor connections.

It’s all about your needs: Depending on the laboratory requirements, the units are customized for use in fume hoods or as mobile units on casters with brakes.

Selected Publication

2017: Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Jonathan E. Phillips, Xuxia Zhang, James A. Johnston