Class II, Type B1—Vertical Flow Biological Safety Cabinet
The Baker Company NCB-D^® Class II, Type B1 Biological Safety Cabinet meets or exceeds specifications for the NCI-1 cabinet developed by the National Cancer Institute.

The NCB-D^® is designed for biological work, product preparation and experimentation involving agents of low and moderate risk (Biosafety Levels 1, 2 or 3).

The cabinet exceeds design requirements of NCI Specification “General Purpose Clean Air Biological Safety Cabinet” (Class II, Type B Safety Cabinet dated July 6, 1976) and National Sanitation Foundation (NSF) International Standard #49.
Applications for Class II, Type B1 cabinets include microbiological studies, cell culture, pharmaceutical procedures and toxicology.
According to NCI, this Class II, Type B1 cabinet may be used for work with chemical carcinogens in microgram quantities (Laboratory Safety Monograph, NIH, January 1979).

NCB-D^®
HEPA-filtered, particle free supply plenum plus approximately 60% direct exhaust from work area helps prevent build-up of chemical vapors and gases.

CSA Listed	Meets NSF Standards	Underwriter Laboratories Listed

NCB-D^® includes additional, unique design features proven to enhance containment while inhibiting cross contamination and exposure to chemicals, vapors and gases.

A high velocity suction channel prevents gases or particles from migrating behind the viewscreen and entering the work area.
Sliding 10,º ergonomically sloped viewscreen provides easy access to the work area.
Mass Airflow Monitor automatically activates an audio/visual alarm if exhaust airflow in the duct decreases below the calibrated set point.
A non-glare satin finish work surface with wide radius corners improves user comfort and simplifies cleaning.
The HEPA filters located below the work surface provide an added measure of protection by eliminating contamination in the blower/motor area and positive pressure areas of the cabinet.
Positive pressure plenums are downstream of HEPA filters and are completely surrounded by negative pressure.
Padded ergonomic arm rest.

The NCB-D^® provides personnel, product and environmental protection plus internal contamination control. The NCB-D^® design and airflow system protects the product by creating a particulate free work area, while minimizing build-up of chemical vapors and gases which pass through HEPA filters.

Used in accordance with proper technique, NCB-D^® provides protection to the environment as well as personnel operating the equipment. In addition, NCB-D^® protects the environment from vapors/gases if exhaust air is specially treated (i.e. catalytic conversion, scrubbing, activated charcoal) and exhausted to the outside.

The high performance airflow system with a circulation-to-exhaust ratio of 40%:60% reduces concentration of chemical vapors and gases inside cabinet.
Double downflow HEPA filters eliminate blower/motor contamination. HEPA filters are positioned above and below the work area. Only HEPA-filtered air is provided to the positive pressure plenum.
The HEPA filter above the work area is rarely changed, if ever, because it is exposed only to HEPA-filtered air as it passes through the positive pressure plenum.
The cabinet is designed for easy HEPA filter replacement and decontamination.
NCB-D^® features a direct exhaust area at the rear of the cabinet. This direct exhaust area provides additional personnel and product protection from gases and vapors by directing this airflow immediately to the exhaust system.

HEPA-filtered air descends through the work zone in a unidirectional (laminar) vertical downflow.
At the approximate center of the work surface, the air splits. Approximately 40% of the air exits to the base of the cabinet via the front perforated grille. The remaining 60% is pulled through the rear exhaust slot.
Escape of potentially harmful agents is prevented in part by an air barrier of inward-flowing room air at the front access opening. Room air entering through the front access opening is drawn into the front perforated grille and does not enter the work area.

In the base of the cabinet, the air drawn through the front perforated grille is pulled by the blower/motor through the primary-downflow HEPA filter and pushed through a plenum to the top of the cabinet.
Upon reaching the top of the cabinet, the air travels through the secondary downflow HEPA filter and re-enters the work area as particle-free laminar flowing air.
Air entering the rear exhaust slot from the work area is drawn directly into the duct at the rear of the cabinet, through the HEPA exhaust filter and into the facility exhaust system.
Baker’s exclusive momentum air curtain contains particles within the work area and inhibits migration of room air into the work area.